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WorldDual-strain Covid vaccine: UK first country to approve

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Dual-strain Covid vaccine: UK first country to approve

The UK has become the first country to approve a dual vaccine that protects against both the older Omicron version and the original Covid virus.

The vaccination, according to ministers, will now be a part of the autumn booster program.

26 million people are eligible for some version of the booster, but Moderna estimates that just 13 million doses of its new vaccine will be made accessible this year.

According to health officials, people should receive any booster that is recommended because all vaccinations offer protection.

The initial pandemic vaccines were created to prepare the body to combat the virus’s first version, which appeared in Wuhan, China, at the end of 2019.

The Covid virus has since mutated substantially, with a stream of new variants emerging that can dodge some of our immune defenses. They have caused large surges in cases around the world.

The original vaccines still provide strong protection against becoming severely ill or dying, but companies are tweaking them to match the virus as it evolves.

Cases of coronavirus are currently falling in the UK. In mid-to-late July, around 2.5 million people tested positive for coronavirus.

‘Sharpened tool’

Moderna’s latest vaccine targets both the original strain and the first Omicron variant (BA.1), which emerged last winter. It is known as a bivalent vaccine as it takes aim at two forms of Covid.

The UK’s Medicines and Healthcare Products Regulatory Agency has considered the evidence and given the vaccine approved for use in adults.

Dr. June Raine, the regulator’s chief executive, said: “What this bivalent vaccine gives us is a sharpened tool in our armory to help protect us against this disease as the virus continues to evolve.”

Experiments on 437 people showed the updated vaccine was safe and gave better immune protection against newer variants.

Levels of antibodies that were able to stick to and disable Omicron (BA.1) were 1.7 times higher in people given the new vaccine. Tests against more recent Omicron variants (BA.4 and BA.5), which are causing the UK’s current wave, also showed higher levels of protection with the updated vaccine.

However, it is far from clear what that means in terms of preventing someone from becoming seriously ill.

Additionally, it is uncertain what variants we will be facing in the coming months and exactly how well the updated vaccine will perform against them.

Stéphane Bancel, the chief executive officer of Moderna, said he was “delighted” the vaccine had been approved.

“This represents the first authorization of an Omicron-containing bivalent vaccine; this bivalent vaccine has an important role to play in protecting people in the UK from Covid-19 as we enter the winter months,” he said.

The Joint Committee on Vaccination and Immunization (JCVI), which advises governments in England, Wales, Northern Ireland, and Scotland, has confirmed the following groups should be offered some form of booster in the autumn:

  • health and social care staff
  • everyone aged 50 and over
  • carers who are over the age of 16
  • people over five whose health puts them at greater risk, this includes pregnant women
  • people over five who share a house with somebody with a weakened immune system

Prof Wei Shen Lim, from the JCVI, said: “It is important that everyone who is eligible takes up a booster this autumn, whichever vaccine is on offer.”

Originally those aged 50-65 were not going to be jabbed. However, the immunization campaign has been expanded because of the rapid spread of variants, uncertainty about how the virus will mutate, and the expectation that we will are likely to be more social – and therefore give the virus a helping hand this winter – including at Christmas.

However, most people under 50 will not be boosted in the coming months. The focus remains on preventing those most at risk from becoming seriously ill, rather than stopping the young from passing the virus on to older relatives.

Moderna is not the only company updating its vaccines. Pfizer has also been developing vaccines that can target Omicron. The Oxford-AstraZeneca vaccine, however, is not being updated.

Health ministers have officially given the go-ahead for the bivalent vaccines. In England, Steve Barclay said “vaccines remain our best defense against Covid” and said the rollout would begin in September. In Wales, Eluned Morgan said vaccines “have saved countless lives” and urged everyone who was eligible to come forward.

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