Governor Valentyn Reznichenko, five kamikaze drones were shot down overnight in the Dnipropetrovsk region of central-eastern Ukraine.
He reported on Telegram that Russia launched more than 50 shells into the city of Nikopol, injuring two persons.
Ten high-rise and private buildings, a transport company, several shops, a garage, cars, and several offices were destroyed.
He said more strikes had hit residential areas of Nikopol on Saturday morning and that details were still coming through.
Ten rockets were also launched this morning at Zaporizhzhia, about 38 miles (61km) to the east, said the region’s governor.
Oleksandr Starukh said on Telegram that a number of energy and industrial infrastructure facilities were destroyed. Information on casualties is so far unclear.
There were also four overnight airstrikes on the city by drones, Mr Starukh added. Fires broke out but no one was injured.