Paintings and sculptures owned by late Microsoft co-founder Paul Allen fetched a record $1.5 billion (£1.3 billion).
According to Christie’s, it was the largest art auction in history.
Works by Vincent van Gogh, Georges Seurat, Paul Gauguin, Paul Cezanne, and Gustav Klimt each sold for more than $100 million (£88 million), according to the auction house, breaking individual records for those artists.
The sale proceeds will be donated to charities that Allen supported before his death in 2018.
The most expensive piece of art bought was Seurat’s 1888 work Les Poseuses, Ensemble (small version), a renowned work of pointillism, which fetched $149.2m (£131m), including fees, Christie’s said.
Experts say the super wealthy are viewing art as a safe investment amid a tumultuous global economy and Russia’s war in Ukraine.
Other record-breaking works included Van Gogh’s Orchard with Cypresses, which fetched $117.2m (£103m); Gauguin’s Maternity II, which sold for $105.7m (£93m); and Klimt’s Birch Forest, which went under the hammer for $104.6m (£92m).
Paintings from Georgia O’Keefe, Claude Monet, David Hockney, Andrew Wyeth and Pablo Picasso were also sold, along with sculptures by Alexander Calder and Max Ernst.
The total value of the collection has already beaten the record set earlier this year, for the Macklowe collection, owned by a wealthy New York couple – which sold for $922m (£810m).
Mr Allen co-founded Microsoft in 1975 with his childhood friend Bill Gates.
He was treated for non-Hodgkin lymphoma in 2009, but it returned, and in 2018 he died from complications of the disease.
In 2010, he pledged to leave the majority of his fortune to charity after his death. At the time he was the 37th richest man in the world, according to Forbes magazine, with an estimated $13.5bn (then £8.8bn).
A further 90 lots from his collection will be sold on Thursday.