The two teams met for the first time since Manchester United defeated Newcastle United 2-0 in the Carabao Cup final at Wembley on February 26.
Casemiro and Marcus Rashford scored in that game.
Using goals from ex-Arsenal player Joe Willock and striker Calum Wilson to defeat the Red Devils 2-0 at St. James Park, Newcastle exacted their retaliation.
The victory put Newcastle ahead of United, who now have a goal advantage despite being tied on points.
If Tottenham defeats Everton later today, the Red Devils could drop out of the top four.
Ten Hag had a blip of his own.
In the 83rd minute, with the scores still at 1-0, he subbed off centre-backs Lisandro Martinez and Raphael Varane, a decision termed bizarre by the Manchester Evening News.
Ten Hag explains defender subs
The Dutch manager’s decision came under scrutiny and Argentine defender, Martinez reacted angrily to the decision by smacking a chair in the dugout, as observed by Sun UK.
The decision did not pay off as Newcastle doubled their lead five minutes later through Wilson.
Ten Hag explained the decision after the game, as quoted by Metro UK: ‘‘We were not happy.
We played too high in midfield and it was easy for their two centre-halves to go and attack.
We had to play a little bit deeper. Therefore we made the sub. Then we made changes to bring more energy,’’ he said.