An unknown number of Senior High School (SHS) students are said to be trapped in an STC bus they were travelling by.
They got involved in an accident on Monday morning after their bus with registration number GT-1079-20 collided with a speeding tipper truck on the Kasoa-Cape Coast highway.
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The STC bus was heading to Cape Coast from Kasoa.
Personnel from the Ghana National Service and other emergency services are at the scene to rescue them, sources say.
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Twenty-five people have been left injured while six others are in critical condition.
According to reports, some of the victims have been rescued while others remained unaccounted for.
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No deaths have been reported so far.
Source: The Independent Ghana